| Bioactivity | RGB110 (Compound 10d) binds to CRBN (Cereblon) through Pomalidomide (HY-10984), exhibits the inhibitory activity against D-dopachrome tautomerase with an IC50 of 5.9 μM[1]. |
| Formula | C40H37F3N8O8 |
| Molar Mass | 814.77 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Osipyan A, et al., The synthesis of 1,2,3-triazoles as binders of D-dopachrome tautomerase (D-DT) for the development of dual-targeting inhibitors. Eur J Med Chem. 2024 Jul 8;276:116665. |