Bioactivity | RET-IN-28 (Compound 16) is a RET (transmembrane receptor tyrosine protein kinase) inhibitor. RET-IN-28 inhibits the activity of the mutant RET enzyme (RET-V804M), and can be applied to cancer research[1]. |
Invitro | RET-IN-28 抑制 RET-V804M 酶活性,抑制率为92% (100 nM)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> RET-IN-28 相关抗体: |
CAS | 2479961-45-8 |
Formula | C26H29N9 |
Molar Mass | 467.57 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chen Z, et al. Heterocyclic compound, pharmaceutical composition comprising same, preparation method therefor, and use thereof. World Intellectual Property Organization, WO2020168939A1. 2020-08-27. |