| Bioactivity | RA-0002034 is a Chikungunya virus (CHIKV) nsP2 protease inhibitor with an IC50 of 58 nM. RA-0002034 covalently modifies the catalytic cysteine in a site-specific manner[1]. |
| Invitro | RA-0002034 是一种含有乙烯基砜弹头的共价片段，可抑制 CHIKV nsP2pro，IC50 为 58 nM。[1]。 在 α 病毒感染的细胞模型中，RA-0002034 可有效抑制 CHIKV 和相关 α 病毒的病毒复制[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> RA-0002034 相关抗体: |
| Formula | C16H19N3O4S |
| Molar Mass | 349.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Eric M Merten, et al. Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach. bioRxiv[Preprint]. 2024 May 23:2024.03.22.586341. |