| Bioactivity | R-(+)-Mono-desmethylsibutramine is the R enantiomer of Mono-desmethylsibutramine. |
| Invitro | Sibutramine, a monoamine reuptake inhibitor, is used as a racemate, for the treatment of obesity. It is converted in vivo mainly to two desmethyl active metabolites, mono-desmethylsibutramine (MDS) and di-desmethylsibutramine (DDS) [1]. |
| Name | R-(+)-Mono-desmethylsibutramine |
| CAS | 229639-54-7 |
| Formula | C16H24ClN |
| Molar Mass | 265.82 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bae K, et al. Analysis of enantiomers of sibutramine and its metabolites in rat plasma by liquid chromatography-mass spectrometry using a chiral stationary-phase column. J Pharm Biomed Anal. 2009 Sep 8;50(2):267-70. |