| Bioactivity | Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum Sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum Sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1[1]. |
| Name | Quorum Sensing-IN-2 |
| CAS | 2925926-80-1 |
| Formula | C19H13F2NO3 |
| Molar Mass | 341.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang P, et al. Design and Synthesis of 4-Fluorophenyl-5-methylene-2(5H)-furanone Derivatives as Potent Quorum Sensing Inhibitors. J Med Chem. 2023 Jul 13;66(13):8441-8463. |
Quorum Sensing-IN-2
CAS: 2925926-80-1 F: C19H13F2NO3 W: 341.31
Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without
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