Quazolast_product_DataBase

Bioactivity	Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers[1][2].
In Vivo	Quazolast (0.2, 1, 5 mg/kg; p.o.) 可减轻无水乙醇 (0.9 mg/kg) 引起的大鼠胃损伤[1]。Quazolast (3.1, 6.3, 12.5, 25 mg/kg; p.o.) 可减轻与 0.6 N HCl 给药相关的胃损伤[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	86048-40-0
Formula	C12H7ClN2O3
Molar Mass	262.65
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Fitzpatrick LR, et al. Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats. Agents Actions. 1991 Jul;33(3-4):330-6. [2]. Dave NK, et al. A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen. Ann Allergy. 1990 Oct;65(4):298-302.

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