| Bioactivity | QYL-685 is a Z-methenylcyclopropane nucleoside analog containing 2,6-diaminopurine, which has strong antiviral activity against HIV-1. QYL-685 showed activity against Zidovudine (HY-17413) resistant and Didanosine (HY-B0249) resistant HIV-1 infected clones in vitro. QYL-685 can be developed as a therapeutic drug for HIV-1 infection[1]. |
| CAS | 210355-14-9 |
| Formula | C20H24N7O5P |
| Molar Mass | 473.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Uchida H, et al. In vitro anti-human immunodeficiency virus activities of Z-and E-methylenecyclopropane nucleoside analogues and their phosphoro-L-alaninate diesters[J]. Antimicrobial agents and chemotherapy, 1999, 43(6): 1487-1490. |