| Bioactivity | QWF Peptide (Compound 4a) is a substance P antagonist with an IC50 of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC50 of 4.7 μM[1]. |
| Target | IC50: 0.09 μM (substance P) |
| Name | QWF Peptide |
| CAS | 126088-82-2 |
| Sequence | {Boc}-Gln-{d-Trp(Formyl)}-Phe-{OBzl} |
| Shortening | {Boc}-Q-{d-Trp(Formyl)}-F-{OBzl} |
| Formula | C38H43N5O8 |
| Molar Mass | 697.78 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hagiwara D, et al. Studies on neurokinin antagonists. 1. The design of novel tripeptides possessing the glutaminyl-D-tryptophylphenylalanine sequence as substance P antagonists. J Med Chem. 1992 May 29;35(11):2015-25. |