| Bioactivity | QN523 is a novel scaffold with drug-like properties, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 induces apoptosis and autophagy. QN523 can be used in research of cancer[1]. |
| Invitro | QN523 (72 h) has cytotoxicity with IC50 values ranging from 0.1 to 5.7 μM across 12 cell lines[1].QN523 (0.1 and 0.5 μM; 24 and 48 h; MIA PaCa-2 cells) arrests cell cycle at S phase and delays for pancreatic cancer cells to enter the G2-M phase. QN523 induces apoptosis and autophagy of MIA PaCa-2 Cells[1]. Cell Cycle Analysis[1] Cell Line: |
| Name | QN523 |
| CAS | 878581-60-3 |
| Formula | C14H10N4O |
| Molar Mass | 250.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |