| Bioactivity | QMT-CBT is a near-infrared aggregation-induced luminescent photon. After activation of caspase1 (Cas1), QMT-CBT undergoes a CBT-Cys click reaction to form a cyclic dimer QMT-Dimer (the first aggregate) and assembles into nanoparticles (the second aggregate), turning the AIE signal "on" to enhance imaging of Alzheimer's disease (AD)[1]. |
| Sequence | Ac-Trp-Glu-His-Asp-{Cys(StBu)}-{Pra(QMT)}-CBT |
| Shortening | Ac-WEHD-{Cys(StBu)-{Pra(QMT)}-CBT |
| Formula | C94H89N19O12S4 |
| Molar Mass | 1805.09 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xu L, et al. Dual Aggregations of a Near-Infrared Aggregation-Induced Emission Luminogen for Enhanced Imaging of Alzheimer's Disease. J Am Chem Soc. 2023 Dec 20;145(50):27748-27756. |