| Bioactivity | QL-1200186 is anorally activeand selective inhibitor ofTYK2. Oral administration of QL-1200186, dose-dependently inhibitsinterferon-γ(IFNγ) production afterinterleukin-12(IL-12) challenge and significantly ameliorates skin lesions in psoriatic mice[1]. |
| Name | QL-1200186 |
| CAS | 2848664-42-4 |
| Formula | C26H27N7O3 |
| Molar Mass | 485.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen CX, et al. A novel highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) can block inflammation- and autoimmune-related pathways. Cell Commun Signal. 2023;21(1):287. Published 2023 Oct 16. |
QL-1200186
CAS: 2848664-42-4 F: C26H27N7O3 W: 485.54
QL-1200186 is anorally activeand selective inhibitor ofTYK2. Oral administration of QL-1200186, dose-dependently inhibit
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