Bioactivity | QGC583 is an effective selective inhibitor of Aminopeptidase A (APA) with an IC50 value of 4 nM. QGC583 can inhibit APA activity in the brain, kidneys, and heart of rats[1]. |
Target | IC50: 4 nM (APA). |
CAS | 2417001-25-1 |
Formula | C13H20NO5P |
Molar Mass | 301.28 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Balavoine F, et al. Rational design, synthesis and pharmacological characterization of novel aminopeptidase A inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 113: 129940. |