| Bioactivity | Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. | ||||||||||||
| Invitro | Pyridoxal 5′-phosphate severely inhibits the DNA Polymerase and RNase H. Pyridoxal phosphate results in an imnediate reduction in the rate of DNA synthesis[1]. Conjugation to pyridoxal phosphate fully inhibits NEIL2. Pyridoxal phosphate-conjugated NEIL2 shows much lower activity than the intact enzyme over a wide range of enzyme/substrate ratios. After Pyridoxal phosphate conjugation, the ability of NEIL2 to bind the THF-ligand is completely lost[2]. | ||||||||||||
| Name | Pyridoxal phosphate | ||||||||||||
| CAS | 54-47-7 | ||||||||||||
| Formula | C8H10NO6P | ||||||||||||
| Molar Mass | 247.14 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Pyridoxal phosphate
CAS: 54-47-7 F: C8H10NO6P W: 247.14
Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for th
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