| Bioactivity | Pyridomycin (Erizomycin) is a selective and low cytotoxic inhibitor of Mycobacterium tuberculosis that effectively targets InhA. Pyrdomycin is also an antibiotic that can be obtained from metabolites of Dactylosporangium fulvum. Pyrdomycin can be used in the study of bacterial infections such as tuberculosis[1][2]. |
| Invitro | Pyridomycin 能有效抑制 Mycobacterium tuberculosis，其最低抑菌浓度为 0.39 µg/mL[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Pyridomycin 相关抗体: |
| CAS | 18791-21-4 |
| Formula | C27H32N4O8 |
| Molar Mass | 540.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hartkoorn RC, et al. Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med. 2012 Oct;4(10):1032-42. [2]. Hartkoorn RC, et al. Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA. Nat Chem Biol. 2014 Feb;10(2):96-8. |