| Bioactivity | Pyrazinib is a inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, inhibiting the secretion of Il-6, Il-4, Il-8 and Il-13 cytokines from in oac radioresistant cells. Pyrazinib inhibits blood vessel development in zebrafish[1]. |
| CAS | 200417-97-6 |
| Formula | C12H10N2O |
| Molar Mass | 198.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Buckley AM, et al. Pyrazinib (P3), [(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma. Cancer Lett. 2019;447:115-129. |