| Bioactivity | Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1]. |
| Invitro | Py-MPB-amino-C3-PBD (compound 73) shows cytotoxicity with IC50s of 301, 144.1 and 37.5 nM for U138-MG, A431, and REH cells, respectively. Py-MPB-amino-C3-PBD possesses potent anti-bacterial effects against the gram negative strain E. coli K12, with potency of 2 pg/mL determined[1]. |
| Name | Py-MPB-amino-C3-PBD |
| CAS | 2412924-07-1 |
| Formula | C41H44N8O6 |
| Molar Mass | 744.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |