| Bioactivity | Purotoxin 1 is a P2X3 receptor inhibitor. Purotoxin 1 shows antinociceptive properties in animal models of inflammatory pain. Purotoxin 1 can be isolated from the venom of the wolf spider Geolycosa sp[1]. |
| Name | Purotoxin 1 |
| CAS | 1396322-38-5 |
| Sequence | Gly-Tyr-Cys-Ala-Glu-Lys-Gly-Ile-Arg-Cys-Asp-Asp-Ile-His-Cys-Cys-Thr-Gly-Leu-Lys-Cys-Lys-Cys-Asn-Ala-Ser-Gly-Tyr-Asn-Cys-Val-Cys-Arg-Lys-Lys-NH2 (Disulfide bridge: Cys3-Cys16, Cys10-Cys21, Cys15-Cys32, Cys23-Cys30) |
| Shortening | GYCAEKGIRCDDIHCCTGLKCKCNASGYNCVCRKK-NH2 (Disulfide bridge: Cys3-Cys16, Cys10-Cys21, Cys15-Cys32, Cys23-Cys30) |
| Formula | C155H249N51O47S8 |
| Molar Mass | 3835.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Grishin EV, et al. Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain. Ann Neurol. 2010 May;67(5):680-3. |
Purotoxin 1
CAS: 1396322-38-5 F: C155H249N51O47S8 W: 3835.47
Purotoxin 1 is a P2X3 receptor inhibitor. Purotoxin 1 shows antinociceptive properties in animal models of inflammatory
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