| Bioactivity | Purine phosphoribosyltransferase-IN-1 (Compound (S,R)-48) is a potent inhibitor of the Plasmodium falciparum (Pf), P. vivax (Pv) and Trypanosoma brucei (Tbr) 6-oxopurine purine phosphoribosyltransferases (PRTs), with Ki values of 50, 20, and 2 nM, respectively[1]. |
| Name | Purine phosphoribosyltransferase-IN-1 |
| Formula | C11H15N5Na4O10P2 |
| Molar Mass | 531.17 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tomáš Klejch, et al. Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases. J Med Chem. 2022 Mar 10;65(5):4030-4057. |
Purine phosphoribosyltransferase-IN-1
CAS: F: C11H15N5Na4O10P2 W: 531.17
Purine phosphoribosyltransferase-IN-1 (Compound (S,R)-48) is a potent inhibitor of the Plasmodium falciparum (Pf), P. vi
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