| Bioactivity | Pulvomycin (Antibiotic 1063Z) is an antibiotic with protein biosynthesis inhibitory activity. Pulvomycin is able to block protein biosynthesis in Bacillus brevis grown in cells. Pulvomycin is highly sensitive to poly(Phe) synthesis in cell-free systems. Pulvomycin does not affect the transfer of phenylalanine to tRNA. Studies have shown that the target of Pulvomycin is the elongation of the polypeptide chain. Pulvomycin can also prevent the formation of a ternary complex between the elongation factor Tu, GTP and aminoacyl-tRNA[1]. |
| CAS | 11006-66-9 |
| Formula | C47H66O13 |
| Molar Mass | 839.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pulvomycin, an inhibitor of prokaryotic protein biosynthesis |