PtdIns-(3,4,5)-P3-biotin sodium_product_DataBase

Bioactivity	PtdIns-(3,4,5)-P3-biotin sodium is a Biotin-labeled PtdIns-(3,4,5)-P3 (PI(3,4,5)P3). PI(3,4,5)P3 is a substrate of nuclear phosphatidylinositol 5-phosphatase (PIP5Pase). PI(3,4,5)P3 binds to the N-terminus of RAP1 (repressor activator protein 1) and controls its DNA binding activity[1].
Invitro	PIP5Pase 瞬时失活会导致核 PI(3,4,5)P3 积累，PI(3,4,5)P3 会结合 RAP1 并将其从表达位点 (ESs) 中取代，从而激活沉默 ESs 的转录和变异表面糖蛋白 (VSG) 切换[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PtdIns-(3,4,5)-P3-biotin sodium 相关抗体:
CAS	1415684-80-8
Formula	C35H61N3Na4O24P4S
Molar Mass	1155.78
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Touray AO, et al. PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes. Elife. 2023 Nov 29;12:RP89331.

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