| Bioactivity | Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth[1][2]. | |||||||||
| Invitro | Psicofuranine specifically inhibits bacterial GMP synthase as demonstrated by isolation of Psicofuranine-resistant Escherichia coli mutants with mutations in the gene encoding GMP synthase and inhibition of bacterial growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth with an IC50 of 0.3 mM. The Psicofuranine inhibitory concentration is similar to that of E. coli[1]. | |||||||||
| Name | Psicofuranine | |||||||||
| CAS | 1874-54-0 | |||||||||
| Formula | C11H15N5O5 | |||||||||
| Molar Mass | 297.27 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
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Psicofuranine
CAS: 1874-54-0 F: C11H15N5O5 W: 297.27
Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also spec
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