| Bioactivity | Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia in diabetic rats. Pruvanserin can also be used for research of insomnia[1]. |
| CAS | 443144-26-1 |
| Formula | C22H21FN4O |
| Molar Mass | 376.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Abbas A, et al. Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders. Expert Opin Pharmacother. 2008 Dec;9(18):3251-9. [2]. Mixcoatl-Zecuatl T, et al. A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy. Br J Pharmacol. 2011 Sep;164(1):159-69. |
Pruvanserin
CAS: 443144-26-1 F: C22H21FN4O W: 376.43
Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia i
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