Bioactivity | Prostaglandin F2α dimethyl amine is a Prostaglandin F2α (HY-12956) derivative. Prostaglandin F2α dimethyl amine is an antagonist for Prostaglandin F receptor (FP)[1]. Prostaglandin F2α dimethyl amine blocks the cardiovascular responses induced by orexin and Arachidonic acid (HY-109590)[2]. |
In Vivo | Prostaglandin F2α dimethyl amine (50 µg,脑室内注射,单剂量) 可预防 Sprague-Dawley 大鼠体内由食欲素和 Arachidonic acid (HY-109590) 引起的升压和心动过速[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 67508-09-2 |
Formula | C22H41NO3 |
Molar Mass | 367.57 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Griffin BW, et al., AL-8810: a novel prostaglandin F2 alpha analog with selective antagonist effects at the prostaglandin F2 alpha (FP) receptor. J Pharmacol Exp Ther. 1999 Sep;290(3):1278-84. [2]. ALTINBAŞ B. The Intermediation Role of Central Cyclooxygenase Products TXA2, PGF2α, PGE, and PGD in Orexin-evoked Cardiovascular Effects[J]. Izmir Democracy University Health Sciences Journal, 2021, 4(3): 251-266. |