Prostaglandin E3_product_DataBase

Bioactivity	Prostaglandin E3 is an eicosanoid derived from eicosapentaenoic acid. Prostaglandin E3 inhibits polarization towards M1 but promotes polarization of M2a macrophages. Prostaglandin E3 shows anti-inflammatory and anti-tumor activity[1].
Invitro	Prostaglandin E3 (1-10000 nM) 在极化巨噬细胞中抑制 M1 并诱导 M2a 标记物表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Prostaglandin E3 相关抗体:
In Vivo	Prostaglandin E3 (1 µmol/L; i.p.) 在 LPS (HY-D1056) (5 mg/kg) 诱导急性炎症模型中调节巨噬细胞极化以发挥抗炎功能[1]。Prostaglandin E3 (1 µmol/L; every 3 days for 4 weeks) 通过调节巨噬细胞极化表现出抗肿瘤活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	802-31-3
Formula	C20H30O5
Molar Mass	350.45
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Cui J, et al. Prostaglandin E3 attenuates macrophage-associated inflammation and prostate tumour growth by modulating polarization. J Cell Mol Med. 2021 Jun;25(12):5586-5601.

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