| Bioactivity | Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. | |||||||||
| Invitro | PGE2 shows inhibition of IL 2 production in the mixture of irradiated and nonirradiated T lymphocytes. PGE2 (0.1-10 μM) dose-dependently inhibits the production of IL 2. PGE2 acts during the inductive phase of activation of suppressor cells. Preincubation of T lymphocytes with PGE2 induces cells that suppress IL 2 production and PHA proliferation[1]. | |||||||||
| Name | Prostaglandin E2 | |||||||||
| CAS | 363-24-6 | |||||||||
| Formula | C20H32O5 | |||||||||
| Molar Mass | 352.47 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
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