Bioactivity | Prostaglandin E2-1-glyceryl ester, a Prostaglandin Glycerol Ester, is an endocannabinoid ligand for the CB1 receptor. Prostaglandin E2-1-glyceryl ester induces rapid, transient elevation of intracellular free Ca2+[1][2]. |
Target | EC50: 150 nM (Ca2+ in NG108-15 cells). |
Invitro | Prostaglandin E2-1-glyceryl ester 在鼠血浆中迅速水解为生成 PGE2 (t1⁄2 = 14 s),但在人血浆中缓慢代谢 (t1⁄2 = 10 min)[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Prostaglandin E2-1-glyceryl ester 相关抗体: |
CAS | 37497-47-5 |
Formula | C23H38O7 |
Molar Mass | 426.54 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. K R Kozak, et al. Metabolism of prostaglandin glycerol esters and prostaglandin ethanolamides in vitro and in vivo. J Biol Chem. 2001 Oct 5;276(40):36993-8. [2]. T Sugiura, et al. 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. Biochem Biophys Res Commun. 1996 Dec 4;229(1):58-64. |