| Bioactivity | Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1][2]. | ||||||||||||
| Invitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | ||||||||||||
| Name | Propargyl-PEG4-Tos | ||||||||||||
| CAS | 875770-32-4 | ||||||||||||
| Formula | C18H26O7S | ||||||||||||
| Molar Mass | 386.46 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Propargyl-PEG4-Tos
CAS: 875770-32-4 F: C18H26O7S W: 386.46
Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavab
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