| Bioactivity | Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | ||||||||||||
| Invitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | ||||||||||||
| Name | Propargyl-PEG4-Br | ||||||||||||
| CAS | 1308299-09-3 | ||||||||||||
| Formula | C11H19BrO4 | ||||||||||||
| Molar Mass | 295.17 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Propargyl-PEG4-Br
CAS: 1308299-09-3 F: C11H19BrO4 W: 295.17
Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleav
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