| Bioactivity | Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | ||||||||||||
| Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. | ||||||||||||
| Name | Propargyl-PEG2-NHBoc | ||||||||||||
| CAS | 869310-84-9 | ||||||||||||
| Formula | C12H21NO4 | ||||||||||||
| Molar Mass | 243.30 | ||||||||||||
| Appearance | Liquid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Nello Mainolfi, et al. rak degraders and uses thereof. US20190192668A1. |
Propargyl-PEG2-NHBoc
CAS: 869310-84-9 F: C12H21NO4 W: 243.30
Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.