Propanoic acid-d5_product_DataBase

Bioactivity	Propanoic acid-d5 is a deuterated labeled Propanoic acid[1]. Propanoic acid can be synthesized into propionates and used as esterification agent, nitrocellulose solvent, plasticizer, chemical reagent and food preparation raw material. Propionates are microbiota-derived metabolites with intestinal immunomodulatory effects on intestinal cholesterol metabolism. Propionates reduce total blood cholesterol and LDL cholesterol levels in animal models. Propionates may control dyslipidemia and prevent atherosclerotic cardiovascular disease (ACVD)[2].
Invitro	氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Propanoic acid-d5 相关抗体:
CAS	60153-92-6
Formula	C3HD5O2
Molar Mass	79.11
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Haghikia A, et al. Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism. Eur Heart J. 2022 Feb 10;43(6):518-533.

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