| Bioactivity | Prolyl Hydroxylase inhibitor 1 (Compound 15i) is an orally active hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) inhibitor with an IC50 of 62.23 nM[1]. Antianemia agent[1]. |
| Target | IC50: 62.23±2.33nM (HIF-PHD) |
| Name | Prolyl Hydroxylase inhibitor 1 |
| CAS | 2205125-60-4 |
| Formula | C19H18ClN5O4 |
| Molar Mass | 415.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wu Y, et al. Click Chemistry-Based Discovery of [3-Hydroxy-5-(1 H-1,2,3-triazol-4-yl)picolinoyl]glycines as Orally Active Hypoxia-Inducing Factor Prolyl Hydroxylase Inhibitors with Favorable Safety Profiles for the Treatment of Anemia. J Med Chem. 2018 Ju |
Prolyl Hydroxylase inhibitor 1
CAS: 2205125-60-4 F: C19H18ClN5O4 W: 415.83
Prolyl Hydroxylase inhibitor 1 (Compound 15i) is an orally active hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD
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