| Bioactivity | Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities. | ||||||||||||
| Invitro | Procyanidin B2 shows antiproliferative activity to MCF-7 cells, with an IC50 of 19.21 μM. However, Procyanidin B2 exhibits no effect on DNA-ladder formation[1]. Procyanidin B2 (0.1, 1, 2 μM) inhibits the activation of pyrin domain containing 3 (NLRP3) inflammasome in human umbilical vein ECs (HUVECs), and the inhibition is via suppression of AP-1 activity, and such effect can be abolished by overexpression of c-Jun. Procyanidin B2 (2 μM for 12 h) also reduces ROS in HUVECs[2]. | ||||||||||||
| Name | Procyanidin B2 | ||||||||||||
| CAS | 29106-49-8 | ||||||||||||
| Formula | C30H26O12 | ||||||||||||
| Molar Mass | 578.52 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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