Bioactivity | Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF)[1]. | |||||||||
Invitro | In-vitro studies show pristinamycin to inhibit Staphylococci and Streptococci, including Erythromycin highly-resistant organisms, at a concentration of less than or equal to 0.78 mg/l[2]. | |||||||||
Name | Pristinamycin | |||||||||
CAS | 270076-60-3 | |||||||||
Formula | C73H89N11O17 | |||||||||
Molar Mass | 1392.55 | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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