| Bioactivity | Pristinamycin IA (Mikamycin B) is a cycle-peptidic macrolactone antibiotic. Pristinamycin IA is a substrate of P-glycoprotein and inhibits its function. Pristinamycin IA is active against StaphyloEoccus and Srreptococcus[1]. | ||||||||||||
| Invitro | Pristinamycin IA (100 μM, 0-4 h) inhibits the efflux of [3H]vinblastine from Caco-2 cells[1].Pristinamycin IA (100 μM) reduces by 70% the basolateral to apical secretion of [3H]vinblastine across Caco-2 cell monolayers[1].Pristinamycin IA (4.614 μM) activates ribosome-dependent ribo-regulator (LRR)[2]. | ||||||||||||
| Name | Pristinamycin IA | ||||||||||||
| CAS | 3131-03-1 | ||||||||||||
| Formula | C45H54N8O10 | ||||||||||||
| Molar Mass | 866.96 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Pristinamycin IA
CAS: 3131-03-1 F: C45H54N8O10 W: 866.96
Pristinamycin IA (Mikamycin B) is a cycle-peptidic macrolactone antibiotic. Pristinamycin IA is a substrate of P-glycopr
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