| Bioactivity | Prilocaine hydrochloride, an amino amide, is a Na, K-ATPase inhibitor. Prilocaine has neurotoxic effects[1][2]. |
| Target | Na, K-ATPase |
| Invitro | Prilocaine hydrochloride is more potent in inhibiting the Na,K-ATPase of plasma membranes of LM cells (transformed fibroblasts) at 37 ℃ (43.8 mM) than at 25 ℃ (28.2 mM)[2]. |
| Name | Prilocaine hydrochloride |
| CAS | 1786-81-8 |
| Formula | C13H21ClN2O |
| Molar Mass | 256.77 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90(3):216-22. [2]. H Kutchai, et al. Effects of local anaesthetics on the activity of the Na,K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41(1):1-7. |
Prilocaine hydrochloride
CAS: 1786-81-8 F: C13H21ClN2O W: 256.77
Prilocaine hydrochloride, an amino amide, is a Na, K-ATPase inhibitor. Prilocaine has neurotoxic effects.
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This product is for research use only, not for human use. We do not sell to patients.