Bioactivity | Prenylamine lactate is a calcium-modulating protein (CaM) antagonist that inhibits CaM-dependent enzymes and can slowly relax smooth muscle preparations. The effect of Prenylamine lactate on smooth muscle is not inhibited by the calcium agonist Bay K 8644 (HY-10588). Reports suggest that under low heart rate conditions, Prenylamine seems to enhance voltage-dependent transmembrane calcium currents[1]. |
CAS | 69-43-2 |
Formula | C27H33NO3 |
Molar Mass | 419.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bayer R, et al. Basic mechanisms underlying prenylamine-induced ‘torsade de pointes’: differences between prenylamine and fendiline due to basic actions of the isomers[J]. Current Medical Research and Opinion, 1988, 11(4): 254-272. |