| Bioactivity | Prazobind (SZL 49), a prazosin analog, is a potent alpha 1-adrenoceptor blocker. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC50=1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes[1][2]. |
| Name | Prazobind |
| CAS | 107021-36-3 |
| Formula | C23H27N5O3 |
| Molar Mass | 421.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mante S, et al. The alkylating prazosin analog SZL 49 inactivates both alpha 1A- and alpha 1B-adrenoceptors. Eur J Pharmacol. 1991;208(2):113-117. [2]. Piascik MT, Kusiak JW, Barron KW. Alpha 1-adrenoceptor subtypes and the regulation of peripheral hemodynamics in the conscious rat. Eur J Pharmacol. 1990;186(2-3):273-278. |
Prazobind
CAS: 107021-36-3 F: C23H27N5O3 W: 421.49
Prazobind (SZL 49), a prazosin analog, is a potent alpha 1-adrenoceptor blocker. Prazobind competes for alpha 1-adrenoce
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