| Bioactivity | Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1]. | ||||||||||||
| Target | EC50: 197 nM (sGC) | ||||||||||||
| Name | Praliciguat | ||||||||||||
| CAS | 1628730-49-3 | ||||||||||||
| Formula | C21H14F8N6O2 | ||||||||||||
| Molar Mass | 534.36 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution. |
Praliciguat
CAS: 1628730-49-3 F: C21H14F8N6O2 W: 534.36
Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as
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