| Bioactivity | PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1]. |
| Target | IC50：1.6 μM (PrPSc) |
| Name | PrPSc-IN-1 |
| CAS | 1315475-30-9 |
| Formula | C22H17N5O |
| Molar Mass | 367.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zaccagnini L, et al. Identification of novel fluorescent probes preventing PrPSc replication in prion diseases. Eur J Med Chem. 2017 Feb 15;127:859-873. |
PrPSc-IN-1
CAS: 1315475-30-9 F: C22H17N5O W: 367.40
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6
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