Bioactivity | Posatirelin, a TRH analog, increases monoamine metabolites in the cerebral cortex, nucleus accumbens,and striatum, and possibly exerts CNS activating effects through a modification of several neurotransmitter systems[1]. |
In Vivo | Posatirelin (2 mg/kg, IP) 增加了3个月和24个月的低氧大鼠中高亲和性 Ca2+-ATP 酶。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 78664-73-0 |
Formula | C17H28N4O4 |
Molar Mass | 352.43 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. G Benzi, et al. Age-related changes by hypoxia and TRH analogue on synaptic ATPase activities. Neurobiol Aging. 1994 Jul-Aug;15(4):409-17. |