Bioactivity | Pomalidomide-C11-NH2 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-C11-NH2 can be connected to the ligand for protein by a linker to form PROTAC[1]. |
Name | Pomalidomide-C11-NH2 |
CAS | 2648285-39-4 |
Formula | C24H34N4O4 |
Molar Mass | 442.55 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chotitumnavee J, et al. Selective degradation of histone deacetylase 8 mediated by a proteolysis targeting chimera (PROTAC). Chem Commun (Camb). 2022 Apr 7;58(29):4635-4638. |