| Bioactivity | Pomalidomide-5'-C8-acid (Compound 3d') is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-5'-C8-acid can be used in the synthesis of PROTACs[1]. |
| Name | Pomalidomide-5'-C8-acid |
| CAS | 2682112-09-8 |
| Formula | C22H27N3O6 |
| Molar Mass | 429.47 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Rao, Yu, et al. Preparation of isoindoline derivatives as degradation agent targeting both BTK and GSPT1 proteins and its application. Patent. CN115304606 |
Pomalidomide-5'-C8-acid
CAS: 2682112-09-8 F: C22H27N3O6 W: 429.47
Pomalidomide-5'-C8-acid (Compound 3d') is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) base
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