Bioactivity | Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs[1]. |
Name | Pomalidomide 4'-PEG6-azide |
CAS | 2624181-62-8 |
Formula | C27H38N6O10 |
Molar Mass | 606.62 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lailiang Qu, et al. Discovery of PT-65 as a highly potent and selective Proteolysis-targeting chimera degrader of GSK3 for treating Alzheimer's disease. Eur J Med Chem. 2021 Dec 15:226:113889. |