Bioactivity | Polθ-IN-4 (Example 1) is a DNA polymerase theta (Polθ) inhibitor that inhibits Polθ activity by targeting its ATP-dependent helicase domain. Polθ-IN-4 can be utilized in cancer research[1]. |
CAS | 3043810-73-4 |
Formula | C17H17ClN5O7PS |
Molar Mass | 501.84 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Janos B, et al. Thiadiazolyl derivatives as dna polymerase theta inhibitors and uses thereof, WO2024121290A1, 2024-06-13 |