| Bioactivity | Polyethylene glycol 12-hydroxystearate, a Macrogol 15 hydroxy stearate, is a permeability enhancer[1]. |
| Invitro | Polyethylene glycol 12-hydroxystearate is used to increase the aqueous solubility of Biopharmaceutical Classification System (BCS) Class 2 and 4 lipophilic molecules. Polyethylene glycol 12-hydroxystearate has shown an enhancement in permeability of medium sized biological drugs across epithelia[1]. |
| Name | Polyethylene glycol 12-hydroxystearate |
| CAS | 61909-81-7 |
| Formula | (C2H4O)nC18H36O3 |
| Appearance | Oil |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture |
| Reference | [1]. Shubber S, et al. Mechanism of mucosal permeability enhancement of CriticalSorb (Solutol HS15) investigated in vitro in cell cultures. Pharm Res. 2015 Feb;32(2):516-27. |
Polyethylene glycol 12-hydroxystearate
CAS: 61909-81-7 F: (C2H4O)nC18H36O3 W:
Polyethylene glycol 12-hydroxystearate, a Macrogol 15 hydroxy stearate, is a permeability enhancer.
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