Bioactivity | Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses. | ||||||||||||
Invitro | Polydatin protects cerebral cells from ischemic damages via improvement of microcirculation and inhibition of platelet aggregation. In addition, polydatin inhibits ICAM-1 expression in endothelial cells stimulated by lipopolysaccharide; it also attenuates adhesion between white blood cells and endothelial cells[1]. Polydatin inhibits cancer cell proliferation and cell cycle progression[4]. Polydatin induces ER stress-driven cell death[4]. | ||||||||||||
Name | Polydatin | ||||||||||||
CAS | 27208-80-6 | ||||||||||||
Formula | C20H22O8 | ||||||||||||
Molar Mass | 390.38 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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