| Bioactivity | Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4]. | ||||||||||||
| Invitro | Pterostilbene (0, 5, 25, 50, 100, 200 and 400 µM) shows inhibitory activity against the growth of HeLa cells, with IC50s of 101.2 µM and 65.9 µM at 24 and 48 hrs, respectively. Ipterostilbene (0, 25, 100 and 200 µM) also induces the apoptosis HeLa cells[2].Pterostilbene (0.05, 0.1, 0.15 and 0.2 mM) has high anti-oxidant activity against DPPH, ABTS, hydroxyl, superoxide, hydrogen peroxide in a dose-dependent manner. Pterostilbene decreases lipid peroxides and hydroperoxides, reduces protein carbonyl groups and restores protein sulphydryl groups in response to damage by TBHP and As-Fe2+. Pterostilbene also inhibits single strand breaks in pBR322[4]. | ||||||||||||
| Name | Pterostilbene | ||||||||||||
| CAS | 537-42-8 | ||||||||||||
| Formula | C16H16O3 | ||||||||||||
| Molar Mass | 256.30 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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