Bioactivity | Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II. | ||||||||||||
Invitro | Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use. | ||||||||||||
Name | Podofilox | ||||||||||||
CAS | 518-28-5 | ||||||||||||
Formula | C22H22O8 | ||||||||||||
Molar Mass | 414.41 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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