| Bioactivity | Poacic Acid is a plant-derived stilbenoid with an antifungal activity. Poacic Acid localizes to the yeast cell wall and disrupts the production and assembly of β-1,3-glucan in the fungal cell walls. Poacic Acid exhibits fungicidal activity to Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants[1]. |
| Invitro | Poacic Acid (0-512 μg/ml; 48 h) 在浓度达到或超过 256 μg/mL 时, 表现出对 Saccharomyces cerevisiae 显著的增长抑制作用。对 ERG11 和 ERG3 基因缺失的 Candida albicans 突变株显示出杀菌效果[1]。Poacic Acid (1 mM; 1-42 h) 增加了 Saccharomyces cerevisiae 细胞壁的几丁质产量，并改变了其分布[1]。Poacic Acid (512 μg/mL; 36 h) 在存在额外的 β- 葡聚糖或几丁质或者金属离子时，对 Saccharomyces cerevisiae 的抑制效果降低[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Poacic acid 相关抗体: |
| CAS | 160097-32-5 |
| Formula | C19H18O6 |
| Molar Mass | 342.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yona A, et al. Poacic Acid, a Plant-Derived Stilbenoid, Augments Cell Wall Chitin Production, but Its Antifungal Activity Is Hindered by This Polysaccharide and by Fungal Essential Metals. Biochemistry. 2024 Apr 16;63(8):1051-1065. |