| Bioactivity | Plocabulin (PM060184) is a potent microtubule inhibitor. Plocabulin is a natural product that could be isolated from the marine sponge Lithoplocamia lithistoides. Plocabulin suppresses microtubule shortening and growth. Plocabulin has anticancer activity[1][2]. |
| Name | Plocabulin |
| CAS | 960210-99-5 |
| Formula | C31H45N3O7 |
| Molar Mass | 571.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Martínez-Díez M, et, al. PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors. Biochem Pharmacol. 2014 Apr 1;88(3):291-302. [2]. Costales-Carrera A, et, al. Plocabulin Displays Strong Cytotoxic Activity in a Personalized Colon Cancer Patient-Derived 3D Organoid Assay. Mar Drugs. 2019 Nov 19;17(11):648. |
Plocabulin
CAS: 960210-99-5 F: C31H45N3O7 W: 571.70
Plocabulin (PM060184) is a potent microtubule inhibitor. Plocabulin is a natural product that could be isolated from the
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